Quantcast
top of page

clinical testing

Significantly decreases the presence of harmful bacteria present in the gut microbiome

tick-dark-green_2x.png

Significantly improves constipation, bloating and abdominal pain

tick-dark-green_2x.png

Significantly reduces blood cholesterol

tick-dark-green_2x.png

Significantly increases the growth of beneficial bacteria in the gut microbiome

tick-dark-green_2x.png

Participants

A study was conducted on 45 human subjects aged between 18 & 65 who defecate less than three times a week and are aware of their own difficulty in defecation.

The participants were randomly split into 3 groups, 15 in the control group, 15 subjects receiving 200mg/day of the root biotics postbiotic, and the final 15 subjects 600mg/day for 30 days.

Methods of analysis

One day prior to the subjects consuming the postbiotics, their defecation symptoms were recorded, stool samples, and blood samples were collected.

After 30 days of continuous consumption of postbiotics, stool and blood samples were collected again to be analysed and compared against the samples taken prior to the start of the study.

An evaluation questionnaire was used for subjects to evaluate any changes in constipation, bloating, and upper and lower abdominal pain.

Overall daily improvement in bowel movements

Overall improvement no_title.png

Results

As patients with constipation often experience certain gastrointestinal symptoms, this study aimed
to discover any changes in the gastrointestinal function in the subjects after consuming 200 mg or 600 mg Root postbiotics every day in comparison to the placebo group.

The results shown in the table above indicated that with consuming 600 mg there was a significant improvement in bowel movements, such as diarrhoea and constipation, whereas other symptoms of gastrointestinal discomfort including upper and lower abdominal pain were also significantly reduced.

 

In addition, gastrointestinal symptoms seem to have been alleviated for those who consumed 200 mg daily compared to the placebo group.

Change rate in bacterial flora in the microbiome

From the bacterial flora of the subjects who consumed 600 mg of Root postbiotics daily, a significant increase in the beneficial probiotic flora Bifidobacterium, Akkermansia, Lactococcus, and Lactobacillus was observed as shown by the green bars in the graph below.

Also, an evident drop in the harmful pathogenic flora Enterococcus and Streptococcus was observed as shown by the red bars in the graph below.

 

For the subjects who consumed 200 mg daily, we observed an increase in both the probiotic and harmful flora,
yet neither reached a significant statistical difference.

 

For the placebo group who consumed no postbiotics, a minor decrease in the probiotic flora was observed.

Flora no_title.png
Science Lab

safety testing

Root daily postbiotics are rigorously tested before being dispatched to our customers. Because we’re so committed to making sure Root meets our strict manufacturing guidelines, each and every
batch is tested to ensure consistency and our customers safety.

 

Our postbiotics are created in a Good Manufacturing Practices (GMP) and ISO22000 HACCP laboratory.

general scientific studies

Postbiotics are defined as the non-viable microbial components or metabolites that confer a health benefit on the host.

 

They are produced by the fermentation of probiotics or other microorganisms. Postbiotics are gaining increasing attention as a potential therapeutic agent for a variety of conditions, including gastrointestinal disorders, allergies and immune dysfunction.

There is a lot of research emerging from around the world to highlight the benefits of postbiotics. In 2022 alone, there were over 1,000 scientific papers published on postbiotics. The results so far are promising.

 

Some of the potential benefits of postbiotics include:

  • Improving gut health and reducing the risk of gastrointestinal disorders

  • Reducing inflammation and allergic reactions

  • Boosting the immune system

  • Protecting against cancer

  • Improving cognitive function

  • Reducing the risk of obesity and diabetes

A list of interesting research articles and papers are listed below:

01

Postbiotics have favourable influence on the host with longer shelf life

03

The short chain fatty acids (SCFAs), vitamins and enzymes in Postbiotics can increase immunity

05

A balanced view of the benefits and safety of Postbiotics

07

Stomach acid destroys Probiotics. L. Rhamnosus GG survival in acidic conditions occurred only in the presence of sugars that it could metabolize efficiently.

09

Postbiotic benefits and how they are available in their raw form and exert targeted health benefits

02

The metabolites in Postbiotics stimulate the growth of the microbiota

04

Probiotics are destroyed in the stomach acid. This study investigates the survival rates of different commercial probiotics.

06

The risks associated with live bacteria (Probiotics) are minimised by Postbiotics

08

Describe the item and add all the relevant details you would like to share. Double click to edit the text and change the description.

bottom of page